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Dr. Chi-Hsuan Chang (章齊軒)

Process Development Scientist

Poseida Therapeutics, CA, USA

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Sean Chang received his Ph.D. in Integrative Molecular and Biomedical Sciences from Baylor College of Medicine. Under the supervision of Dr. Jeffrey Rosen, he discovered the molecular mechanisms underlying the radiation resistance of breast cancer stem cells using preclinical syngeneic mouse models. He then further studied the relationship between chemotherapy efficacy and T cell infiltration in solid tumors during his postdoctoral training.

Sean began his career in industry as a Cell Biology R&D Scientist at Thermo Fisher Scientific in 2016. He worked on multiple product developments to facilitate next generation cell therapy workflow, including improving gene editing efficiency in T cells and developing new automation systems to support both autologous and allogeneic cell therapies. In addition to scientific works, as a project leader, Sean worked closely with other business sectors to ensure a successful product launch. He also played an important role to support business development, technical consultation, and customer facing to increase cell therapy business revenue.

Sean is now a Process Development Scientist at Poseida Therapeutics, a clinical-stage biopharmaceutical company committed to developing novel cell therapy products.

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